The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases

Hydrogen peroxide is an important regulator of protein tyrosine phosphatase activity via reversible oxidation. However, the role of iron in this reaction has not been yet elucidated. Here we compare the influence of hydrogen peroxide and the ferrous iron (reagent for Fenton reaction) on the enzymati...

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Detalles Bibliográficos
Autores principales: Kuban-Jankowska, Alicja, Gorska, Magdalena, Jaremko, Lukasz, Jaremko, Mariusz, Tuszynski, Jack A., Wozniak, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635172/
https://www.ncbi.nlm.nih.gov/pubmed/26407665
http://dx.doi.org/10.1007/s10534-015-9882-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635172/
https://www.ncbi.nlm.nih.gov/pubmed/26407665
http://dx.doi.org/10.1007/s10534-015-9882-4

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