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Non-linear leak currents affect mammalian neuron physiology

In their seminal works on squid giant axons, Hodgkin, and Huxley approximated the membrane leak current as Ohmic, i.e., linear, since in their preparation, sub-threshold current rectification due to the influence of ionic concentration is negligible. Most studies on mammalian neurons have made the s...

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Detalles Bibliográficos
Autores principales: Huang, Shiwei, Hong, Sungho, De Schutter, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635211/
https://www.ncbi.nlm.nih.gov/pubmed/26594148
http://dx.doi.org/10.3389/fncel.2015.00432