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Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis
Amyotrophic lateral sclerosis (ALS) is characterized by massive loss of motor neurons. Data from ALS patients and experimental models indicate that mitochondria are severely damaged within dying or spared motor neurons. Nonetheless, recent data indicate that mitochondrial preservation, although prev...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635226/ https://www.ncbi.nlm.nih.gov/pubmed/26594150 http://dx.doi.org/10.3389/fncel.2015.00434 |