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Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis

Amyotrophic lateral sclerosis (ALS) is characterized by massive loss of motor neurons. Data from ALS patients and experimental models indicate that mitochondria are severely damaged within dying or spared motor neurons. Nonetheless, recent data indicate that mitochondrial preservation, although prev...

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Detalles Bibliográficos
Autores principales:	Natale, Gianfranco, Lenzi, Paola, Lazzeri, Gloria, Falleni, Alessandra, Biagioni, Francesca, Ryskalin, Larisa, Fornai, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635226/ https://www.ncbi.nlm.nih.gov/pubmed/26594150 http://dx.doi.org/10.3389/fncel.2015.00434

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