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Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery

The spread of Plasmodium falciparum multidrug resistance highlights the urgency to discover new targets and chemical scaffolds. Unfortunately, lack of experimentally validated functional information about most P. falciparum genes remains a strategic hurdle. Chemogenomic profiling is an established t...

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Detalles Bibliográficos
Autores principales: Pradhan, Anupam, Siwo, Geoffrey H., Singh, Naresh, Martens, Brian, Balu, Bharath, Button-Simons, Katrina A., Tan, Asako, Zhang, Min, Udenze, Kenneth O., Jiang, Rays H.Y., Ferdig, Michael T., Adams, John H., Kyle, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635350/
https://www.ncbi.nlm.nih.gov/pubmed/26541648
http://dx.doi.org/10.1038/srep15930