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Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery
The spread of Plasmodium falciparum multidrug resistance highlights the urgency to discover new targets and chemical scaffolds. Unfortunately, lack of experimentally validated functional information about most P. falciparum genes remains a strategic hurdle. Chemogenomic profiling is an established t...
Autores principales: | Pradhan, Anupam, Siwo, Geoffrey H., Singh, Naresh, Martens, Brian, Balu, Bharath, Button-Simons, Katrina A., Tan, Asako, Zhang, Min, Udenze, Kenneth O., Jiang, Rays H.Y., Ferdig, Michael T., Adams, John H., Kyle, Dennis E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635350/ https://www.ncbi.nlm.nih.gov/pubmed/26541648 http://dx.doi.org/10.1038/srep15930 |
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