Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Telomeres are nucleoprotein structures at the end of chromosomes which stabilize and protect them from nucleotidic degradation and end-to-end fusions. The G-rich telomeric single-stranded DNA overhang can adopt a four-stranded G-quadruplex DNA structure (G4). Stabilization of the G4 structure by bin...

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Detalles Bibliográficos
Autores principales: Merle, Patrick, Gueugneau, Marine, Teulade-Fichou, Marie-Paule, Müller-Barthélémy, Mélanie, Amiard, Simon, Chautard, Emmanuel, Guetta, Corinne, Dedieu, Véronique, Communal, Yves, Mergny, Jean-Louis, Gallego, Maria, White, Charles, Verrelle, Pierre, Tchirkov, Andreï
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635363/
https://www.ncbi.nlm.nih.gov/pubmed/26542881
http://dx.doi.org/10.1038/srep16255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635363/
https://www.ncbi.nlm.nih.gov/pubmed/26542881
http://dx.doi.org/10.1038/srep16255

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