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Targeted, noninvasive blockade of cortical neuronal activity

Here we describe a novel method to noninvasively modulate targeted brain areas through the temporary disruption of the blood-brain barrier (BBB) via focused ultrasound, enabling focal delivery of a neuroactive substance. Ultrasound was used to locally disrupt the BBB in rat somatosensory cortex, and...

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Detalles Bibliográficos
Autores principales: McDannold, Nathan, Zhang, Yongzhi, Power, Chanikarn, Arvanitis, Costas D., Vykhodtseva, Natalia, Livingstone, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635366/
https://www.ncbi.nlm.nih.gov/pubmed/26542745
http://dx.doi.org/10.1038/srep16253