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Regulation of multispanning membrane protein topology via post-translational annealing
The canonical mechanism for multispanning membrane protein topogenesis suggests that protein topology is established during cotranslational membrane integration. However, this mechanism is inconsistent with the behavior of EmrE, a dual-topology protein for which the mutation of positively charged lo...
Autores principales: | Van Lehn, Reid C, Zhang, Bin, Miller, Thomas F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635508/ https://www.ncbi.nlm.nih.gov/pubmed/26408961 http://dx.doi.org/10.7554/eLife.08697 |
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