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High-frequency, precise modification of the tomato genome

BACKGROUND: The use of homologous recombination to precisely modify plant genomes has been challenging, due to the lack of efficient methods for delivering DNA repair templates to plant cells. Even with the advent of sequence-specific nucleases, which stimulate homologous recombination at predefined...

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Detalles Bibliográficos
Autores principales: Čermák, Tomáš, Baltes, Nicholas J., Čegan, Radim, Zhang, Yong, Voytas, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635538/
https://www.ncbi.nlm.nih.gov/pubmed/26541286
http://dx.doi.org/10.1186/s13059-015-0796-9