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Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice

Dendritic cells (DCs) are powerful APCs that can induce Ag-specific adaptive immune responses and are increasingly recognized as important players in innate immunity to both infection and malignancy. Interestingly, although there are multiple described hematological malignancies, DC cancers are rare...

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Detalles Bibliográficos
Autores principales: Böttcher, Jan P., Zelenay, Santiago, Rogers, Neil C., Helft, Julie, Schraml, Barbara U., Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635568/
https://www.ncbi.nlm.nih.gov/pubmed/26459350
http://dx.doi.org/10.4049/jimmunol.1500889