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Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice
Dendritic cells (DCs) are powerful APCs that can induce Ag-specific adaptive immune responses and are increasingly recognized as important players in innate immunity to both infection and malignancy. Interestingly, although there are multiple described hematological malignancies, DC cancers are rare...
Autores principales: | Böttcher, Jan P., Zelenay, Santiago, Rogers, Neil C., Helft, Julie, Schraml, Barbara U., Reis e Sousa, Caetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635568/ https://www.ncbi.nlm.nih.gov/pubmed/26459350 http://dx.doi.org/10.4049/jimmunol.1500889 |
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