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T cell deficiency in spinal cord injury: altered locomotor recovery and whole-genome transcriptional analysis

BACKGROUND: T cells undergo autoimmunization following spinal cord injury (SCI) and play both protective and destructive roles during the recovery process. T cell-deficient athymic nude (AN) rats exhibit improved functional recovery when compared to immunocompetent Sprague–Dawley (SD) rats following...

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Detalles Bibliográficos
Autores principales: Satzer, David, Miller, Catherine, Maxon, Jacob, Voth, Joseph, DiBartolomeo, Christina, Mahoney, Rebecca, Dutton, James R., Low, Walter C., Parr, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635574/
https://www.ncbi.nlm.nih.gov/pubmed/26546062
http://dx.doi.org/10.1186/s12868-015-0212-0