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Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells

BACKGROUND: Viral infection causes multiple forms of human cancer, and HPV infection is the primary factor in cervical carcinomas. Recent single-cell RNA-seq studies highlight the tumor heterogeneity present in most cancers, but virally induced tumors have not been studied. HeLa is a well characteri...

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Detalles Bibliográficos
Autores principales: Wu, Liang, Zhang, Xiaolong, Zhao, Zhikun, Wang, Ling, Li, Bo, Li, Guibo, Dean, Michael, Yu, Qichao, Wang, Yanhui, Lin, Xinxin, Rao, Weijian, Mei, Zhanlong, Li, Yang, Jiang, Runze, Yang, Huan, Li, Fuqiang, Xie, Guoyun, Xu, Liqin, Wu, Kui, Zhang, Jie, Chen, Jianghao, Wang, Ting, Kristiansen, Karsten, Zhang, Xiuqing, Li, Yingrui, Yang, Huanming, Wang, Jian, Hou, Yong, Xu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635585/
https://www.ncbi.nlm.nih.gov/pubmed/26550473
http://dx.doi.org/10.1186/s13742-015-0091-4