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Systematic Tracking of Disrupted Modules Identifies Altered Pathways Associated with Congenital Heart Defects in Down Syndrome

BACKGROUND: This work aimed to identify altered pathways in congenital heart defects (CHD) in Down syndrome (DS) by systematically tracking the dysregulated modules of reweighted protein-protein interaction (PPI) networks. MATERIAL/METHODS: We performed systematic identification and comparison of mo...

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Detalles Bibliográficos
Autores principales: Chen, Denghong, Zhang, Zhenhua, Meng, Yuxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635630/
https://www.ncbi.nlm.nih.gov/pubmed/26524729
http://dx.doi.org/10.12659/MSM.896001