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In silico characterization and Molecular modeling of double-strand break repair protein MRE11 from Phoenix dactylifera v deglet nour

BACKGROUND: DNA double-strand breaks (DSBs) are highly cytotoxic and mutagenic. MRE11 plays an essential role in repairing DNA by cleaving broken ends through its 3′ to 5′ exonuclease and single-stranded DNA endonuclease activities. METHODS: The present study aimed to in silico characterization and...

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Detalles Bibliográficos
Autores principales: Rekik, Imen, Chaabene, Zayneb, Grubb, C. Douglas, Drira, Noureddine, Cheour, Foued, Elleuch, Amine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635681/
https://www.ncbi.nlm.nih.gov/pubmed/26541955
http://dx.doi.org/10.1186/s12976-015-0013-2