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Association of Extrarenal Adverse Effects of Posttransplant Immunosuppression With Sex and ABCB1 Haplotypes

Extrarenal adverse effects (AEs) associated with calcineurin inhibitor (CNI) and mycophenolic acid (MPA) occur frequently but are unpredictable posttransplant complications. AEs may result from intracellular CNI accumulation and low activity of P-glycoprotein, encoded by the ABCB1 gene. Since ABCB1...

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Detalles Bibliográficos
Autores principales: Venuto, Rocco C., Meaney, Calvin J., Chang, Shirley, Leca, Nicolae, Consiglio, Joseph D., Wilding, Gregory E., Brazeau, Daniel, Gundroo, Aijaz, Nainani, Neha, Morse, Sarah E., Cooper, Louise M., Tornatore, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635790/
https://www.ncbi.nlm.nih.gov/pubmed/26376376
http://dx.doi.org/10.1097/MD.0000000000001315