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Tuberculosis vaccine development: Shifting focus amid increasing development challenges

A new tuberculosis vaccine is needed to replace or enhance BCG, which induces variable protection against Mycobacterium tuberculosis pulmonary infections in adults. Development of new TB vaccine candidates is severely hampered by the lack of a correlate of immunity, unproven animal models, and limit...

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Detalles Bibliográficos
Autores principales: Graves, AJ, Hokey, DA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635864/
https://www.ncbi.nlm.nih.gov/pubmed/26125249
http://dx.doi.org/10.1080/21645515.2015.1040955