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Tuberculosis vaccine development: Shifting focus amid increasing development challenges
A new tuberculosis vaccine is needed to replace or enhance BCG, which induces variable protection against Mycobacterium tuberculosis pulmonary infections in adults. Development of new TB vaccine candidates is severely hampered by the lack of a correlate of immunity, unproven animal models, and limit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635864/ https://www.ncbi.nlm.nih.gov/pubmed/26125249 http://dx.doi.org/10.1080/21645515.2015.1040955 |