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Immunomodulation of the tumor microenvironment by neutralization of Semaphorin 4D
Semaphorin 4D is highly expressed at the invasive tumor margin and acts as a guidance molecule, restricting movement of tumoricidal immune cells into the tumor microenvironment. We recently showed that antibody neutralization of SEMA4D augmented activated monocyte and anticancer T-cell tumor penetra...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635900/ https://www.ncbi.nlm.nih.gov/pubmed/26587332 http://dx.doi.org/10.1080/2162402X.2015.1054599 |