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Identifying activating mutations in the EGFR gene: prognostic and therapeutic implications in non-small cell lung cancer

Lung cancer is the leading cause of cancer-related deaths worldwide. Promising new therapies have recently emerged from the development of molecular targeted drugs; particularly promising are those blocking the signal transduction machinery of cancer cells. One of the most widely studied cell signal...

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Detalles Bibliográficos
Autores principales: Lopes, Gabriel Lima, Vattimo, Edoardo Filippo de Queiroz, de Castro, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635957/
https://www.ncbi.nlm.nih.gov/pubmed/26398757
http://dx.doi.org/10.1590/S1806-37132015000004531