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Complete haplotype phasing of the MHC and KIR loci with targeted HaploSeq

BACKGROUND: The MHC and KIR loci are clinically relevant regions of the genome. Typing the sequence of these loci has a wide range of applications including organ transplantation, drug discovery, pharmacogenomics and furthering fundamental research in immune genetics. Rapid advances in biochemical a...

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Detalles Bibliográficos
Autores principales: Selvaraj, Siddarth, Schmitt, Anthony D., Dixon, Jesse R., Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636068/
https://www.ncbi.nlm.nih.gov/pubmed/26541200
http://dx.doi.org/10.1186/s12864-015-1949-7