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Complete haplotype phasing of the MHC and KIR loci with targeted HaploSeq
BACKGROUND: The MHC and KIR loci are clinically relevant regions of the genome. Typing the sequence of these loci has a wide range of applications including organ transplantation, drug discovery, pharmacogenomics and furthering fundamental research in immune genetics. Rapid advances in biochemical a...
Autores principales: | Selvaraj, Siddarth, Schmitt, Anthony D., Dixon, Jesse R., Ren, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636068/ https://www.ncbi.nlm.nih.gov/pubmed/26541200 http://dx.doi.org/10.1186/s12864-015-1949-7 |
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