Programmed death 1 blockade, an Achilles heel for MMR-deficient tumors?

Program death receptor-1 (PD-1) is upregulated in many tumors and in tumor microenvironment, and PD-1 blockade has led to remarkable immune-based anti-tumor responses in across many tumor types. Pembrolizumab, an anti-programmed death 1 checkpoint inhibitor, resulted in a high rate of immune respons...

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Detalles Bibliográficos
Autores principales: Lin, Andy Yingjie, Lin, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636069/
https://www.ncbi.nlm.nih.gov/pubmed/26542241
http://dx.doi.org/10.1186/s13045-015-0222-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636069/
https://www.ncbi.nlm.nih.gov/pubmed/26542241
http://dx.doi.org/10.1186/s13045-015-0222-5

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