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Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing

Ubiquitination of the replication clamp proliferating cell nuclear antigen (PCNA) at the conserved residue lysine (K)164 triggers postreplicative repair (PRR) to fill single-stranded gaps that result from stalled DNA polymerases. However, it has remained elusive as to whether cells engage PRR in res...

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Detalles Bibliográficos
Autores principales: Becker, Jordan R., Pons, Carles, Nguyen, Hai Dang, Costanzo, Michael, Boone, Charles, Myers, Chad L., Bielinsky, Anja-Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636136/
https://www.ncbi.nlm.nih.gov/pubmed/26545110
http://dx.doi.org/10.1371/journal.pgen.1005659