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Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing
Ubiquitination of the replication clamp proliferating cell nuclear antigen (PCNA) at the conserved residue lysine (K)164 triggers postreplicative repair (PRR) to fill single-stranded gaps that result from stalled DNA polymerases. However, it has remained elusive as to whether cells engage PRR in res...
Autores principales: | Becker, Jordan R., Pons, Carles, Nguyen, Hai Dang, Costanzo, Michael, Boone, Charles, Myers, Chad L., Bielinsky, Anja-Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636136/ https://www.ncbi.nlm.nih.gov/pubmed/26545110 http://dx.doi.org/10.1371/journal.pgen.1005659 |
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