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Connecting Replication and Repair: YoaA, a Helicase-Related Protein, Promotes Azidothymidine Tolerance through Association with Chi, an Accessory Clamp Loader Protein

Elongating DNA polymerases frequently encounter lesions or structures that impede progress and require repair before DNA replication can be completed. Therefore, directing repair factors to a blocked fork, without interfering with normal replication, is important for proper cell function, and it is...

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Detalles Bibliográficos
Autores principales: Brown, Laura T., Sutera, Vincent A., Zhou, Shen, Weitzel, Christopher S., Cheng, Yisha, Lovett, Susan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636137/
https://www.ncbi.nlm.nih.gov/pubmed/26544712
http://dx.doi.org/10.1371/journal.pgen.1005651