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Amphipols Outperform Dodecylmaltoside Micelles in Stabilizing Membrane Protein Structure in the Gas Phase

[Image: see text] Noncovalent mass spectrometry (MS) is emerging as an invaluable technique to probe the structure, interactions, and dynamics of membrane proteins (MPs). However, maintaining native-like MP conformations in the gas phase using detergent solubilized proteins is often challenging and...

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Detalles Bibliográficos
Autores principales: Calabrese, Antonio N., Watkinson, Thomas G., Henderson, Peter J. F., Radford, Sheena E., Ashcroft, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636139/
https://www.ncbi.nlm.nih.gov/pubmed/25495802
http://dx.doi.org/10.1021/ac5037022