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Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment

Celastrol (CL), a triterpenoid extracted from the Chinese herb Tripterygium wilfordii, has recently attracted interest for its potential antitumor effects. However, unfavorable physicochemical and pharmacokinetics properties such as low solubility, poor bioavailability, and systemic toxicity, are li...

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Detalles Bibliográficos
Autores principales: Sanna, Vanna, Chamcheu, Jean Christopher, Pala, Nicolino, Mukhtar, Hasan, Sechi, Mario, Siddiqui, Imtiaz Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636169/
https://www.ncbi.nlm.nih.gov/pubmed/26586945
http://dx.doi.org/10.2147/IJN.S93752