IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus

Interferon Regulatory Factors (IRFs) play fundamental roles in dendritic cell (DC) differentiation and function. In particular, IRFs are critical transducers of TLR signaling and dysregulation in this family of factors is associated with the development of autoimmune disorders such as Systemic Lupus...

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Detalles Bibliográficos
Autores principales: Manni, Michela, Gupta, Sanjay, Nixon, Briana G., Weaver, Casey T., Jessberger, Rolf, Pernis, Alessandra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636285/
https://www.ncbi.nlm.nih.gov/pubmed/26544714
http://dx.doi.org/10.1371/journal.pone.0141927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636285/
https://www.ncbi.nlm.nih.gov/pubmed/26544714
http://dx.doi.org/10.1371/journal.pone.0141927

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