Evolution of Robustness to Protein Mistranslation by Accelerated Protein Turnover

Translational errors occur at high rates, and they influence organism viability and the onset of genetic diseases. To investigate how organisms mitigate the deleterious effects of protein synthesis errors during evolution, a mutant yeast strain was engineered to translate a codon ambiguously (mistra...

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Detalles Bibliográficos
Autores principales: Kalapis, Dorottya, Bezerra, Ana R., Farkas, Zoltán, Horvath, Peter, Bódi, Zoltán, Daraba, Andreea, Szamecz, Béla, Gut, Ivo, Bayes, Mónica, Santos, Manuel A. S., Pál, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636289/
https://www.ncbi.nlm.nih.gov/pubmed/26544557
http://dx.doi.org/10.1371/journal.pbio.1002291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636289/
https://www.ncbi.nlm.nih.gov/pubmed/26544557
http://dx.doi.org/10.1371/journal.pbio.1002291

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