Sonic Hedgehog Signaling: Evidence for Its Protective Role in Endotoxin Induced Acute Lung Injury in Mouse Model

OBJECTIVE: To investigate the protective role of the sonic hedgehog (SHH) signaling associated with a lipopolysaccharide (LPS)-induced acute lung injury (ALI) in a mouse model. METHODS: Male BALB/c mice were randomly divided into four groups: control, LPS, LPS-cyclopamine group and cyclopamine group...

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Detalles Bibliográficos
Autores principales: Chen, Xing, Jin, Yuting, Hou, Xiaoming, Liu, Fengqin, Wang, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636314/
https://www.ncbi.nlm.nih.gov/pubmed/26545089
http://dx.doi.org/10.1371/journal.pone.0140886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636314/
https://www.ncbi.nlm.nih.gov/pubmed/26545089
http://dx.doi.org/10.1371/journal.pone.0140886

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