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Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor

The thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is member of the leucine-rich repeat subfamily (LGR). In the absence of crystal structure, the success of rational design of ligands targeting the receptor internal cavity depends on the quality of the TSHR models built. In...

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Detalles Bibliográficos
Autores principales: Chantreau, Vanessa, Taddese, Bruck, Munier, Mathilde, Gourdin, Louis, Henrion, Daniel, Rodien, Patrice, Chabbert, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636318/
https://www.ncbi.nlm.nih.gov/pubmed/26545118
http://dx.doi.org/10.1371/journal.pone.0142250