Synergistic Effect and Molecular Mechanism of Homoharringtonine and Bortezomib on SKM-1 Cell Apoptosis

BACKGROUND: Myelodysplastic syndromes (MDS) are clonal marrow stem-cell disorders with a high risk of progression to acute myeloid leukemia (AML). Treatment options are limited and targeted therapies are not available for MDS. In the present study, we investigated the cytotoxicity and the molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jing, Chen, Bobin, Wu, Ting, Wang, Qian, Zhuang, Lin, Zhu, Chen, Fan, Ni, Qing, Wenjiao, Ma, Yan, Xu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636319/
https://www.ncbi.nlm.nih.gov/pubmed/26544558
http://dx.doi.org/10.1371/journal.pone.0142422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636319/
https://www.ncbi.nlm.nih.gov/pubmed/26544558
http://dx.doi.org/10.1371/journal.pone.0142422

Ejemplares similares