p31(comet)-Induced Cell Death Is Mediated by Binding and Inactivation of Mad2

Mad2, a key component of the spindle checkpoint, is closely associated with chromosomal instability and poor prognosis in cancer. p31(comet) is a Mad2-interacting protein that serves as a spindle checkpoint silencer at mitosis. In this study, we showed that p31(comet)-induced apoptosis and senescenc...

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Detalles Bibliográficos
Autores principales: Shin, Hyun-Jin, Park, Eun-Ran, Yun, Sun-Hee, Kim, Su-Hyeon, Jung, Won-Hee, Woo, Seon Rang, Joo, Hyun-Yoo, Jang, Su Hwa, Chung, Hee Yong, Hong, Sung Hee, Cho, Myung-Haing, Park, Joong-Jean, Yun, Miyong, Lee, Kee-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636321/
https://www.ncbi.nlm.nih.gov/pubmed/26544187
http://dx.doi.org/10.1371/journal.pone.0141523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636321/
https://www.ncbi.nlm.nih.gov/pubmed/26544187
http://dx.doi.org/10.1371/journal.pone.0141523

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