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Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress

Members of the family of calcium dependent protein kinases (CDPK’s) are abundant in certain pathogenic parasites and absent in mammalian cells making them strong drug target candidates. In the obligate intracellular parasite Toxoplasma gondii TgCDPK3 is important for calcium dependent egress from th...

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Detalles Bibliográficos
Autores principales: Gaji, Rajshekhar Y., Johnson, Derrick E., Treeck, Moritz, Wang, Mu, Hudmon, Andy, Arrizabalaga, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636360/
https://www.ncbi.nlm.nih.gov/pubmed/26544049
http://dx.doi.org/10.1371/journal.ppat.1005268