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Differential Effects of C1qa Ablation on Glaucomatous Damage in Two Sexes in DBA/2NNia Mice
PURPOSE: To determine the sex and age-related effects of C1qa ablation on retinal ganglion cell (RGC) and optic nerve (ON) axonal loss in a mouse model of glaucomatous neurodegeneration. METHODS: Congenic C1qa mice were generated in the DBA/2NNia background. Female and male knockout (-/-), heterozyg...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636422/ https://www.ncbi.nlm.nih.gov/pubmed/26544197 http://dx.doi.org/10.1371/journal.pone.0142199 |