Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive neoplasm characterized by a marked fibro-inflammatory microenvironment(1), the presence of which can promote both cancer induction and growth(2–4). Therefore, selective manipulation of local cytokines is an attractive if unrealized thera...

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Detalles Bibliográficos
Autores principales: Alam, Muhammad S., Gaida, Matthias M., Bergmann, Frank, Lasitschka, Felix, Giese, Thomas, Giese, Nathalia A., Hackert, Thilo, Hinz, Ulf, Hussain, S. Perwez, Kozlov, Serguei V., Ashwell, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636461/
https://www.ncbi.nlm.nih.gov/pubmed/26479921
http://dx.doi.org/10.1038/nm.3957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636461/
https://www.ncbi.nlm.nih.gov/pubmed/26479921
http://dx.doi.org/10.1038/nm.3957

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