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Chemokine Adjuvanted Electroporated-DNA Vaccine Induces Substantial Protection from Simian Immunodeficiency Virus Vaginal Challenge

There have been encouraging results for the development of an effective HIV vaccine. However, many questions remain regarding the quality of immune responses and the role of mucosal antibodies. We addressed some of these issues by using a simian immunodeficiency virus (SIV) DNA vaccine adjuvanted wi...

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Detalles Bibliográficos
Autores principales: Kutzler, M A, Wise, M C, Hutnick, N A, Moldoveanu, Z, Hunter, M, Reuter, M, Yuan, S, Yan, J, Ginsberg, A, Sylvester, A, Pahar, B, Carnathan, D, Kathuria, N, Khan, A S, Montefiori, D, Sardesai, N Y, Betts, M R, Mestecky, J, Marx, P, Weiner, D B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636490/
https://www.ncbi.nlm.nih.gov/pubmed/25943275
http://dx.doi.org/10.1038/mi.2015.31