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CFTR Knockdown induces proinflammatory changes in intestinal epithelial cells

BACKGROUND: Hyperinflammation is a hallmark feature of cystic fibrosis (CF) airways. However, inflammation has also been documented systemically and, more recently, in extrapulmonary CF-affected tissues such as the pancreas and intestine. The pathogenesis of CF-related inflammation and more specific...

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Detalles Bibliográficos
Autores principales: Crites, Karoline St-Martin, Morin, Geneviève, Orlando, Valérie, Patey, Natacha, Cantin, Catherine, Martel, Judith, Brochiero, Emmanuelle, Mailhot, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636765/
https://www.ncbi.nlm.nih.gov/pubmed/26549988
http://dx.doi.org/10.1186/s12950-015-0107-y