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MiR-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45α

BACKGROUND: MicroRNAs (miR, miRNAs) play pivotal roles in numerous physiological and pathophysiological contexts. We investigated whether miR-362-5p act as an oncogene in chronic myeloid leukaemia (CML) and aimed to understand its potential underlying mechanisms. METHODS: We compared the miR-362-5p...

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Detalles Bibliográficos
Autores principales: Yang, Peng, Ni, Fang, Deng, Rui-qing, Qiang, Guo, Zhao, Hua, Yang, Ming-zhen, Wang, Xin-yi, Xu, You-zhi, Chen, Li, Chen, Dan-lei, Chen, Zhi-jun, Kan, Li-xin, Wang, Si-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636774/
https://www.ncbi.nlm.nih.gov/pubmed/26545365
http://dx.doi.org/10.1186/s12943-015-0465-3