Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia

BACKGROUND: Acute promyelocytic leukemia (APL) is associated with chromosomal translocation t(15;17), which results in the proliferation of morphologically abnormal promyelocytes. Gain of supernumerary copies of the 8q24 chromosomal region, which harbors MYC and PVT1, has been shown to be the most c...

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Detalles Bibliográficos
Autores principales: Zeng, Chengwu, Yu, Xibao, Lai, Jing, Yang, Lijiang, Chen, Shaohua, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636781/
https://www.ncbi.nlm.nih.gov/pubmed/26545364
http://dx.doi.org/10.1186/s13045-015-0223-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636781/
https://www.ncbi.nlm.nih.gov/pubmed/26545364
http://dx.doi.org/10.1186/s13045-015-0223-4

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