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Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice

BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease marked by both B and T cell hyperactivity which commonly affects the joints, skin, kidneys, and brain. Neuropsychiatric disease affects about 40 % of SLE patients, most frequently manifesting as depression, memory de...

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Detalles Bibliográficos
Autores principales: Stock, Ariel D., Wen, Jing, Doerner, Jessica, Herlitz, Leal C., Gulinello, Maria, Putterman, Chaim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636802/
https://www.ncbi.nlm.nih.gov/pubmed/26546449
http://dx.doi.org/10.1186/s12974-015-0423-4