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Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice
BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease marked by both B and T cell hyperactivity which commonly affects the joints, skin, kidneys, and brain. Neuropsychiatric disease affects about 40 % of SLE patients, most frequently manifesting as depression, memory de...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636802/ https://www.ncbi.nlm.nih.gov/pubmed/26546449 http://dx.doi.org/10.1186/s12974-015-0423-4 |