Cargando…
Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice
BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease marked by both B and T cell hyperactivity which commonly affects the joints, skin, kidneys, and brain. Neuropsychiatric disease affects about 40 % of SLE patients, most frequently manifesting as depression, memory de...
Autores principales: | Stock, Ariel D., Wen, Jing, Doerner, Jessica, Herlitz, Leal C., Gulinello, Maria, Putterman, Chaim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636802/ https://www.ncbi.nlm.nih.gov/pubmed/26546449 http://dx.doi.org/10.1186/s12974-015-0423-4 |
Ejemplares similares
-
The MRL/lpr Mouse Strain as a Model for Neuropsychiatric Systemic Lupus Erythematosus
por: Gulinello, Maria, et al.
Publicado: (2011) -
Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling
por: Mike, Elise V., et al.
Publicado: (2018) -
B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus
por: Wen, Jing, et al.
Publicado: (2016) -
TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus
por: Doerner, Jessica, et al.
Publicado: (2015) -
Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice
Publicado: (1981)