Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells

BACKGROUND: Tip60 (KAT5) is the histone acetyltransferase (HAT) of the mammalian Tip60/NuA4 complex. While Tip60 is important for early mouse development and mouse embryonic stem cell (mESC) pluripotency, the function of Tip60 as reflected in a genome-wide context is not yet well understood. RESULTS...

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Detalles Bibliográficos
Autores principales: Ravens, Sarina, Yu, Changwei, Ye, Tao, Stierle, Matthieu, Tora, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636812/
https://www.ncbi.nlm.nih.gov/pubmed/26550034
http://dx.doi.org/10.1186/s13072-015-0039-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636812/
https://www.ncbi.nlm.nih.gov/pubmed/26550034
http://dx.doi.org/10.1186/s13072-015-0039-z

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