Practical impacts of genomic data “cleaning” on biological discovery using surrogate variable analysis

BACKGROUND: Genomic data production is at its highest level and continues to increase, making available novel primary data and existing public data to researchers for exploration. Here we explore the consequences of “batch” correction for biological discovery in two publicly available expression dat...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaffe, Andrew E., Hyde, Thomas, Kleinman, Joel, Weinbergern, Daniel R., Chenoweth, Joshua G., McKay, Ronald D., Leek, Jeffrey T., Colantuoni, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636836/
https://www.ncbi.nlm.nih.gov/pubmed/26545828
http://dx.doi.org/10.1186/s12859-015-0808-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636836/
https://www.ncbi.nlm.nih.gov/pubmed/26545828
http://dx.doi.org/10.1186/s12859-015-0808-5

Ejemplares similares