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Primary myeloma interaction and growth in coculture with healthy donor hematopoietic bone marrow

BACKGROUND: Human primary myeloma (MM) cells do not survive in culture; current in vitro and in vivo systems for growing these cells are limited to coculture with a specific bone marrow (BM) cell type or growth in an immunodeficient animal model. The purpose of the study is to establish an interacti...

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Detalles Bibliográficos
Autores principales: Bam, Rakesh, Khan, Sharmin, Ling, Wen, Randal, Shelton S., Li, Xin, Barlogie, Bart, Edmondson, Ricky, Yaccoby, Shmuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636897/
https://www.ncbi.nlm.nih.gov/pubmed/26545722
http://dx.doi.org/10.1186/s12885-015-1892-7