PI3K/AKT/mTOR/p70S6K Pathway Is Involved in Aβ25-35-Induced Autophagy

Disruption or deregulation of the autophagy system has been implicated in neurodegenerative disorders such as Alzheimer's disease (AD). Aβ plays an important role in this autophagic system. In many cases, autophagy is regulated by the phosphatidylinositol 3-phosphate kinase/AKT/mammalian target...

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Detalles Bibliográficos
Autores principales: Fan, Shengnuo, Zhang, Bei, Luan, Ping, Gu, Beibei, Wan, Qing, Huang, Xiaoyun, Liao, Wang, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637023/
https://www.ncbi.nlm.nih.gov/pubmed/26583091
http://dx.doi.org/10.1155/2015/161020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637023/
https://www.ncbi.nlm.nih.gov/pubmed/26583091
http://dx.doi.org/10.1155/2015/161020

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