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Loss of flfl Triggers JNK-Dependent Cell Death in Drosophila

falafel (flfl) encodes a Drosophila homolog of human SMEK whose in vivo functions remain elusive. In this study, we performed gain-of-function and loss-of-function analysis in Drosophila and identified flfl as a negative regulator of JNK pathway-mediated cell death. While ectopic expression of flfl...

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Detalles Bibliográficos
Autores principales: Huang, Jiuhong, Xue, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637051/
https://www.ncbi.nlm.nih.gov/pubmed/26583122
http://dx.doi.org/10.1155/2015/623573