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Loss of flfl Triggers JNK-Dependent Cell Death in Drosophila
falafel (flfl) encodes a Drosophila homolog of human SMEK whose in vivo functions remain elusive. In this study, we performed gain-of-function and loss-of-function analysis in Drosophila and identified flfl as a negative regulator of JNK pathway-mediated cell death. While ectopic expression of flfl...
Autores principales: | Huang, Jiuhong, Xue, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637051/ https://www.ncbi.nlm.nih.gov/pubmed/26583122 http://dx.doi.org/10.1155/2015/623573 |
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